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  6. Insulin Receptor (α-Subunit) Ab-1 Mouse Monoclonal Antibody, Epredia™

Insulin Receptor (α-Subunit) Ab-1 Mouse Monoclonal Antibody, Epredia™

Catalog No. MS631P0 Shop All Epredia Products
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Quantity:
100 μL
200 μL
500 μL
1 mL
Conjugate:
Biotin
Unconjugated
Concentration:
1mg/mL
200μg/mL
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Catalog No. Quantity Conjugate Concentration
MS631P0 100 μL Unconjugated 200μg/mL
MS631P1 500 μL Unconjugated 200μg/mL
MS631P1ABX 100 μL Unconjugated 1mg/mL
MS631PABX 200 μL Unconjugated 1mg/mL
MS631B0 100 μL Biotin 200μg/mL
MS631B1 500 μL Biotin 200μg/mL
MS631B 1 mL Biotin 200μg/mL
MS631P 1 mL Unconjugated 200μg/mL
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Description

Epredia™ Insulin Receptor (α-Subunit) Ab-1, Mouse Monoclonal Antibody provides accurate, reproducible results.

The human insulin receptor is a heterotetrameric membrane glycoprotein consisting of disulfide-linked subunits in a Β-α-α-Β configuration. The Β-subunit (95kDa) possesses a single transmembrane domain, whereas the α-subunit (135kDa) is completely extracellular.

Host Species: Mouse

Clone: 83-14

Isotype: IgG2a/κ

Species Reactivity: Human. Weakly with Cow, Pig and Sheep. Does not react with rabbit, mouse and rat. Others not known.

Epitope: aa 469-592 (exon 7/8)

Immunogen: IM-9 lymphocytes followed by purified insulin receptor

Molecular Weight: 135kDa

Positive Control: IM-9 lymphocyte cells, Placenta

Cellular Localization: Membrane Ab-1 inhibits insulin binding and mimics insulin action. It is excellent for immunoprecipitation of alpha-subunit of IR.

Recommended for:

  • Immunoprecipitation
  • ELISA
  • Insulin-like Agonist
  • Inhibits (∽80%) Insulin Binding (10nM)
  • Tyrosine Kinase Assay (Ab-mediated capture on microplates)

Note:

USA: RUO; Int'l: RUO

Specifications

Antigen Insulin Receptor (alpha-Subunit) Ab-1
Applications Immunoprecipitation
Classification Monoclonal
Clone 83-14
Concentration 200μg/mL
Conjugate Unconjugated
Host Species Mouse
Immunogen IM-9 lymphocytes followed by purified insulin receptor
Quantity 100 μL
Regulatory Status RUO
Research Discipline Steroids Hormones and Growth Factors
Primary or Secondary Primary
Target Species Human
Form Concentrated
Isotype IgG2a κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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