Insulin Receptor (β-subunit) Ab-5 Mouse Monoclonal Antibody, Epredia™

Epredia™ Insulin Receptor (β-Subunit) Ab-5, Mouse Monoclonal Antibody provides accurate, reproducible results.

Supplier:  Epredia MS635P1ABX

Catalog No. MS635P1ABX

Description

The human insulin receptor is a heterotetrameric membrane glycoprotein consisting of disulfide-linked subunits in a Β-α-α-Β configuration. The Β-subunit (95kDa) possesses a single transmembrane domain with tyrosine kinase acivity, whereas the α-subunit (135kDa) is completely extracellular.

Host Species: Mouse

Clone: CT-1

Isotype: IgG1/κ

Species Reactivity: Human, Mouse and Rat.

Epitope: aa-GRVLTLPRS- within the C-terminus

Immunogen: A 15-mer synthetic peptide corresponding to aa Tyr-KKNGRILTLPRSNPS from the C-terminal of human insulin receptor β-subunit

Molecular Weight: 95kDa

Positive Control: IM-9 lymphocyte cells

Cellular Localization: Membrane Ab-5 reacts with autophosphorylated and unoccupied receptors as well as the receptor-insulin complex. Ab-5 does not affect insulin-stimulated autophosphorylation.

Recommended for:

• Immunoprecipitation
• Affinity Purification (With peptide elution)
• ELISA (As capture antibody only)
• Tyrosine Kinase Assay (Ab-mediated capture on microplates)

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: Insulin Receptor (beta-Subunit) Ab-5
• Classification: Monoclonal
• Concentration: 1mg/mL
• Host Species: Mouse
• Quantity: 100 μL
• Research Discipline: Steroids Hormones and Growth Factors
• Target Species: Human, Mouse, Rat
• Isotype: IgG2a κ

• Applications: Immunoprecipitation
• Clone: CT-1
• Conjugate: Unconjugated
• Immunogen: A 15-mer synthetic peptide corresponding to aa Tyr-KKNGRILTLPRSNPS from the C-terminal of human insulin receptor Beta-subunit
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Concentrated