Ku (p70) Ab-4 Mouse Monoclonal Antibody, Epredia™

Recommended for multiple molecular biology techniques, Epredia™ Ku (p70) Ab-4, Mouse Monoclonal Antibody provides accurate, reproducible results.

Supplier:  Epredia MS329PABX

Catalog No. MS329PABX

Description

The Ku autoantigen is a heterodimer of 70kDa (p70) and ∽80kDa (p80) proteins. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase that phosphorylates certain transcription factors, including Sp1, Oct-1, p53, and SV40 large T antigen in vitro. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.

Host Species: Mouse

Clone: N3H10

Isotype: IgG2b

Species Reactivity: Human, Monkey and Xenopus. Mouse and Hamster (Western Blotting only). Does not react with cow, rabbit and sea urchin.

Epitope: aa 506-541

Immunogen: Human placental extract designated as PSE1-PL

Molecular Weight: 70kDa

Positive Control: BT474, T47D, HEP-G-2 or HeLa cells; Tonsil

Cellular Localization: Nuclear

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Western Blotting
• Immunofluorescence
• Immunoprecipitation (Native and denatured)

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: Ku (p70) Ab-4
• Classification: Monoclonal
• Concentration: 1mg/mL
• Host Species: Mouse
• Quantity: 200 μL
• Research Discipline: DNA Repair
• Target Species: Human, Non-human Primate, Xenopus species
• Isotype: IgG2b

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Clone: N3H10
• Conjugate: Unconjugated
• Immunogen: Human placental extract designated as PSE1-PL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Concentrated