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Description
p56lck is a membrane-associated non-receptor protein tyrosine kinase from the Src-family of kinases. The phosphorylation status and the activity of p56lck is regulated by the CD45 tyrosine protein phosphatase. p56lck plays a critical role in T cell development and activation. p56lck gene is localized to a site in the genome which undergoes frequent chromosomal abnormalities in lymphomas and neuroblastomas.
Host Species: Mouse
Clone: 3A5
Isotype: IgG2b/κ
Species Reactivity: Human, Mouse and Rat. Others not known.
Epitope: aa 1-225
Immunogen: Recombinant protein corresponding to aa 1-225 of murine p56lck protein
Molecular Weight: 56kDa
Positive Control: Jurkat cells
Cellular Localization: Cell membrane
Recommended for:
- Western Blotting
- Immunoprecipitation (Denatured verified)
- Kinase Assay
Note:
USA: RUO; Int'l: RUO
Specifications
Specifications
| Antigen | LCK (p56superscriptlcksuperscript) Ab-1 |
| Applications | Immunoprecipitation, Western Blot |
| Classification | Monoclonal |
| Clone | 3A5 |
| Concentration | 1mg/mL |
| Conjugate | Unconjugated |
| Host Species | Mouse |
| Immunogen | Recombinant protein corresponding to aa 1-225 of murine p56superscriptlcksuperscript protein |
| Quantity | 100 μL |
| Regulatory Status | RUO |
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