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  6. LRP/MVP (Major Vault Protein) Ab-2 Mouse Monoclonal Antibody, Epredia™

LRP/MVP (Major Vault Protein) Ab-2 Mouse Monoclonal Antibody, Epredia™

Catalog No. MS664P1ABX Shop All Epredia Products
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Quantity:
100 μL
200 μL
500 μL
1 mL
7 mL
Conjugate:
Biotin
Unconjugated
Concentration:
1mg/mL
200μg/mL
Prediluted
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Catalog No. Quantity Conjugate Concentration
MS664P1ABX 100 μL Unconjugated 1mg/mL
MS664PABX 200 μL Unconjugated 1mg/mL
MS664P1 500 μL Unconjugated 200μg/mL
MS664P 1 mL Unconjugated 200μg/mL
MS664R7 7 mL Unconjugated Prediluted
MS664B0 100 μL Biotin 200μg/mL
MS664B1 500 μL Biotin 200μg/mL
MS664B 1 mL Biotin 200μg/mL
MS664P0 100 μL Unconjugated 200μg/mL
MS664R1 1 mL Unconjugated Prediluted
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Description

Recommended for a variety of techniques, Epredia™ LRP/MVP (Major Vault Protein) Ab-2, Mouse Monoclonal Antibody provides accurate, reproducible results.

Major vault protein (MVP) is identical to lung-resistance related protein (LRP). Its shape is reminiscent of the nucleopore central plug. Treatment of cells with estradiol increases the amount of MVP in nuclear extract. The hormone-dependent interaction of vaults with ER is prevented in vitro by sodium molybdate. Antibodies to progesterone and glucocorticoid receptors are also able to co-immunoprecipitate the MVP. Reportedly, the lung-resistance related protein (LRP) is identical to human MVP. LRP is overexpressed in many neoplastic tissues and cell lines indicating a poor response to chemotherapy.

Host Species: Mouse

Clone: 1032

Isotype: IgG1/κ

Species Reactivity: Human and Rat. Others not known.

Epitope: Not determined

Immunogen: Proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells

Molecular Weight: 104-110kDa

Positive Control: SKBR-3 cells, Breast tumors

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Native verified)
  • Gel Supershift
  • Flow Cytometry

Note:

USA: RUO; Int'l: RUO

Specifications

Antigen LRP/MVP (Major Vault Protein) Ab-2
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 1032
Concentration 1mg/mL
Conjugate Unconjugated
Host Species Mouse
Immunogen Proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells
Quantity 100 μL
Regulatory Status RUO
Research Discipline Cancer and Tumor Biology
Primary or Secondary Primary
Target Species Human, Rat
Form Concentrated
Isotype IgG2a κ
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