MHC II (HLA-DR) Ab-1 Mouse Monoclonal Antibody, Epredia™

Epredia™ MHC II (HLA-DR) Ab-1, Mouse Monoclonal Antibody provides accurate, reproducible results.

Supplier:  Epredia MS133P1ABX

Catalog No. MS133P1ABX

Description

HLA-DR, like other MHC class II molecules, is a transmembrane glycoprotein composed of an α chain (36 kDa) and a β chain (27 kDa). It is expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, thymic epithelial cells and activated T lymphocytes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They therefore have a critical role in the initiation of the immune response.

Host Species: Mouse

Clone: LN3

Isotype: IgG2b

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Activated human peripheral blood mononuclear cells

Molecular Weight: 36kDa (α-chain) and 27kDa (β-chain)

Positive Control: Tonsil/lymph node

Cellular Localization: Membrane

Recommended for:

• Immunohistochemistry
• Flow Cytometry

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: MHC II (HLA-DR) Ab-1
• Classification: Monoclonal
• Concentration: 1mg/mL
• Host Species: Mouse
• Quantity: 100 μL
• Research Discipline: Hematopoietic
• Target Species: Human
• Isotype: IgG2b

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin)
• Clone: LN3
• Conjugate: Unconjugated
• Immunogen: Activated human peripheral blood mononuclear cells
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Concentrated