MMP-2 (72kDa Collagenase IV) Ab-1 Mouse Monoclonal Antibody, Epredia™

Ensure accurate, reproducible results in experiments with the Epredia™ MMP-2 (72kDa Collagenase IV) Ab-1, Mouse Monoclonal Antibody.

Supplier:  Epredia MS567B0

Catalog No. MS567B0

Description

MMPs are proteolytic enzymes capable of degrading connective tissue components. They have a common mode of activation, a conserved amino acid sequence in the putative metal binding-active site region, and are inhibited by specific tissue inhibitors of metalloproteinases (TIMPs). MMPs and TIMPs play a significant role in regulating angiogenesis. MMP-2; also known as 72kDa collagenase IV or gelatinase A is synthesized as a 631 amino acid proenzyme which is activated by cleavage of the first 80 amino acids into an active form.of 62kDa.

Host Species: Mouse

Clone: CA-4001 or CA719E3C

Isotype: IgG1

Species Reactivity: Human, Mouse and Rat. Others not known.

Epitope: N-terminal (APSPIIKFPGD-VAPKTDK)

Immunogen: N-terminal peptide APSPIIKFPGD-VAPKTDK of procollagenase IV

Molecular Weight: 72kDa (proform)

Positive Control: Conditioned, serum-free medium from (TPA-treated) HFL-1 cells

Cellular Localization: Cytoplasmic

Recommended for:

• Western Blotting
• Immunoprecipitation (Not suitable)
• Inhibition of MMP-2 Activity

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: MMP-2 (72kDa Collagenase IV) Ab-1
• Classification: Monoclonal
• Concentration: 200μg/mL
• Host Species: Mouse
• Quantity: 100 μL
• Research Discipline: Proteases And Inhibitors
• Target Species: Human, Mouse, Rat
• Isotype: IgG1

• Applications: Western Blot
• Clone: CA-4001 or CA719E3C
• Conjugate: Biotin
• Immunogen: N-terminal peptide APSPIIKFPGD-VAPKTDK of procollagenase IV
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Concentrated