MMP-2 (72kDa Collagenase IV) Ab-2 Mouse Monoclonal Antibody, Epredia™

Epredia™ MMP-2 (72kDa Collagenase IV) Ab-2, Mouse Monoclonal Antibody provides accurate, reproducible results.

Supplier:  Epredia MS804P0

Catalog No. MS804P0

Description

MMPs are proteolytic enzymes capable of degrading connective tissue components. They have a common mode of activation, a conserved amino acid sequence in the putative metal binding-active site region, and are inhibited by specific tissue inhibitors of metalloproteinases (TIMPs). MMPs and TIMPs play a significant role in regulating angiogenesis. MMP-2; also known as 72kDa collagenase IV or gelatinase A is synthesized as a 631 amino acid proenzyme which is activated by cleavage of the first 80 amino acids.

Host Species: Mouse

Clone: VB3

Isotype: IgG1/κ

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Human native 72kDa MMP-2

Molecular Weight: 72kDa (proform) and ∽66kDa (active form)

Positive Control: Conditioned, serum-free medium from (TPA-treated) HFL-1 cells

Cellular Localization: Cytoplasmic

Recommended for:

• Immunohistochemistry (Not Suitable)
• Western Blotting
• Immunofluorescence
• Immunoprecipitation (Native verified)

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: MMP-2 (72kDa Collagenase IV) Ab-2
• Classification: Monoclonal
• Concentration: 200μg/mL
• Host Species: Mouse
• Quantity: 100 μL
• Research Discipline: Proteases And Inhibitors
• Target Species: Human
• Isotype: IgG2a κ

• Applications: Immunofluorescence, Immunoprecipitation, Western Blot
• Clone: VB3
• Conjugate: Unconjugated
• Immunogen: Human native 72kDa MMP-2
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Concentrated