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  6. p170/p-Glycoprotein/MDR Ab-2 Mouse Monoclonal Antibody, Epredia™

p170/p-Glycoprotein/MDR Ab-2 Mouse Monoclonal Antibody, Epredia™

Catalog No. MS660P1 Shop All Epredia Products
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Quantity:
100 μL
200 μL
500 μL
1 mL
Concentration:
1mg/mL
200μg/mL
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Catalog No. Quantity Concentration
MS660P1 500 μL 200μg/mL
MS660P1ABX 100 μL 1mg/mL
MS660P 1 mL 200μg/mL
MS660PABX 200 μL 1mg/mL
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Description

Ensure accurate, reproducible results with the Epredia™ p170/p-Glycoprotein/MDR Ab-2, Mouse Monoclonal Antibody.

Multi-drug resistance(MDR) associated p-glycoprotein (p170) causes resistance to various drugs in a number of cancer patients. It exists in a soluble and membrane associated form. Soluble P-glycoprotein is detected in extracellular fluids of cancer patients, such as malignant ascites and serum. The Mr of soluble P-glycoprotein is the same as that of membrane bound P-glycoprotein.

Host Species: Mouse

Clone: F4

Isotype: IgG1

Species Reactivity: Human, Chinese Hamster. Does not react with mouse. Others not known.

Epitope: Extracellular amino terminal half. This epitope is resistant to formalin fixation and periodate oxidation and is different from those of other commonly known MAbs to p-glycoprotein, such as C219, JSB-1, and MRK16, which recognize an intracellular and extracellular epitope of p-glycoprotein, respectively.

Immunogen: Human and hamster drug-resistant viable cells followed by crude plasma membranes

Molecular Weight: 170kDa

Positive Control: Drug-resistant cells, Kidney or breast CA

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Flow Cytometry (Fixed cells only)

Note:

USA: RUO; Int'l: RUO

Specifications

Antigen p170/p-Glycoprotein/MDR Ab-2
Applications Immunofluorescence, Western Blot
Classification Monoclonal
Clone F4
Concentration 200μg/mL
Conjugate Unconjugated
Host Species Mouse
Immunogen Human and hamster drug-resistant viable cells followed by crude plasma membranes
Quantity 500 μL
Regulatory Status RUO
Research Discipline Cancer and Tumor Biology
Primary or Secondary Primary
Target Species Hamster, Human
Form Concentrated
Isotype IgG1
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