Learn More
p170/p-Glycoprotein/MDR Ab-2 Mouse Monoclonal Antibody, Epredia™
Ensure accurate, reproducible results with the Epredia™ p170/p-Glycoprotein/MDR Ab-2, Mouse Monoclonal Antibody.
Supplier: Epredia MS660P1
Description
Multi-drug resistance(MDR) associated p-glycoprotein (p170) causes resistance to various drugs in a number of cancer patients. It exists in a soluble and membrane associated form. Soluble P-glycoprotein is detected in extracellular fluids of cancer patients, such as malignant ascites and serum. The Mr of soluble P-glycoprotein is the same as that of membrane bound P-glycoprotein.Host Species: Mouse
Clone: F4
Isotype: IgG1
Species Reactivity: Human, Chinese Hamster. Does not react with mouse. Others not known.
Epitope: Extracellular amino terminal half. This epitope is resistant to formalin fixation and periodate oxidation and is different from those of other commonly known MAbs to p-glycoprotein, such as C219, JSB-1, and MRK16, which recognize an intracellular and extracellular epitope of p-glycoprotein, respectively.
Immunogen: Human and hamster drug-resistant viable cells followed by crude plasma membranes
Molecular Weight: 170kDa
Positive Control: Drug-resistant cells, Kidney or breast CA
Cellular Localization: Membrane
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunofluorescence
- Flow Cytometry (Fixed cells only)
Note:
USA: RUO; Int'l: RUO
Specifications
p170/p-Glycoprotein/MDR Ab-2 | |
Monoclonal | |
200μg/mL | |
Mouse | |
500 μL | |
Cancer and Tumor Biology | |
Hamster, Human | |
IgG1 |
Immunofluorescence, Western Blot | |
F4 | |
Unconjugated | |
Human and hamster drug-resistant viable cells followed by crude plasma membranes | |
RUO | |
Primary | |
Concentrated |
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.