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p21 WAF1 Ab-11 Mouse Monoclonal Antibody, Epredia™
Ensure accurate, reproducible results with the Epredia™ p21WAF1 Ab-11, Mouse Monoclonal Antibody.
Supplier: Epredia MS891P0
Description
p21WAF1/Cip1/Sdi1/Pic1 is a tumor suppressor protein. Expression of p21WAF1 is induced by wild type, but not mutant, p53 suppressor protein. The p21WAF1 protein binds to cyclin/CDK complexes and inhibits their kinase activity thereby stopping cell cycle progression. It also binds to PCNA (proliferating cell nuclear antigen) and blocks DNA replication but not the DNA repair process.Host Species: Mouse
Clone: CP74
Isotype: IgG2b
Species Reactivity: Human and Rat. Others not known.
Epitope: aa 1-80
Immunogen: Full-length human recombinant p21 protein
Molecular Weight: 21kDa
Positive Control: Raji, PC12 cells
Cellular Localization: Nuclear
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunoprecipitation (Native verified)
- Flow Cytometry
Note:
USA: RUO; Int'l: RUO
Specifications
| p21superscriptWAF1superscript Ab-11 | |
| Monoclonal | |
| 200μg/mL | |
| Mouse | |
| 100 μL | |
| Cell Cycle | |
| Human, Rat | |
| IgG2b |
| Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| CP74 | |
| Unconjugated | |
| Full length human recombinant p21 protein | |
| RUO | |
| Primary | |
| Concentrated |
Safety and Handling
WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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