p53 Ab-5 Mouse Monoclonal Antibody, Epredia™

Achieve accurate, reproducible results with the Epredia™ p53 Ab-5, Mouse Monoclonal Antibody.

Supplier:  Epredia MS186P1ABX

Catalog No. MS186P1ABX

Description

p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.

Host Species: Mouse

Clone: DO-7

Isotype: IgG2b/κ

Species Reactivity: Human, Monkey, Cow. Others not known.

Epitope: aa 37-45

Immunogen: Recombinant human wild-type p53 protein expressed in E. coli

Molecular Weight: 53kDa

Positive Control: SKBR-3 or MDA-231 cells, Colon CA

Cellular Localization: Nuclear

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Western Blotting
• Immunofluorescence
• Immunoprecipitation (Denatured verified)
• Flow Cytometry

Specifications

• Antigen: p53 Ab-5
• Classification: Monoclonal
• Conjugate: Unconjugated
• Immunogen: Recombinant human wild-type p53 protein expressed in E. coli
• Regulatory Status: IVD
• Primary or Secondary: Primary
• Form: Concentrated

• Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Clone: DO-7
• Host Species: Mouse
• Quantity: 100 μL
• Research Discipline: Cancer and Tumor Biology
• Target Species: Bovine, Human, Non-human Primate
• Isotype: IgG2b κ