Epredia™ Lab Vision™ p53 Rabbit Monoclonal Antibody (Clone SP5)

Employ part of a comprehensive antibody portfolio with the Epredia™ p53, Rabbit Monoclonal Antibody (Clone SP5). Studies show rabbit monoclonal antibodies are more sensitive and specific than other available markers.

Supplier:  Epredia™ RM9105S0

Catalog No. RM9105S0

Description

p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.

Host Species: Rabbit

Clone: SP5

Isotype: IgG

Species Reactivity: Human. Others not tested.

Epitope: Not determined

Immunogen: Recombinant human full-length wild type p53 protein

Molecular Weight: 53kDa

Positive Control: MDA-231 cells, Colon CA

Cellular Localization: Nuclear

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Western Blotting

Specifications

• Antigen: p53
• Classification: Monoclonal
• Conjugate: Unconjugated
• Immunogen: Recombinant human full-length wild type p53 protein
• Regulatory Status: IVD
• Primary or Secondary: Primary
• Form: Concentrated

• Applications: Western Blot
• Clone: SP5
• Host Species: Rabbit
• Quantity: 100 μL
• Research Discipline: Cancer and Tumor Biology
• Target Species: Human
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov