Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. Epredia™ Lab Vision™ p53 Rabbit Monoclonal Antibody (Clone Y5)

Epredia™ Lab Vision™ p53 Rabbit Monoclonal Antibody (Clone Y5)

Catalog No. RM2103R7 Shop All Epredia Products
Change view
Click to view available options
Quantity:
100 μL
1 mL
7 mL
12 mL
Form:
Concentrated
Prediluted
Ready-to-Use
5 product options available for selection
Product selection table with 5 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity Form
RM2103R7 7 mL Prediluted
RM2103S0 100 μL Concentrated
RM2103S 1 mL Concentrated
RM2103R1 1 mL Prediluted
RM2103RQ 12 mL Ready-to-Use
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 5 options available.
5 options
Catalog No. RM2103R7 Supplier Epredia™ Supplier No. RM2103R7

Description

Employ part of a comprehensive antibody portfolio with the Epredia™ p53, Rabbit Monoclonal Antibody (Clone Y5).

p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein. p53 senses DNA damage and possibly facilitaes repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma. p53 is detected by immunostains only if the mutation causes protein stability (although protein may be nonfunctional) or a physiologic response. The physiologic response may be due to genetic changes induced by cellular stress from anoxia or aneuploidy; or genetic damage to other pathways controlling p53 such as MDM2 or alternative reading frame.

Host Species: Rabbit

Clone: Y5

Species Reactivity: Human.Others not known.

Immunogen: A synthetic peptide derived from N- terminal residues of human p53

Molecular Weight: 53kDa

Positive Control: Colon or Breast CA

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

Specifications

Antigen p53
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone Y5
Conjugate Unconjugated
Host Species Rabbit
Immunogen A synthetic peptide derived from N- terminal residues of human p53
Quantity 7 mL
Regulatory Status IVD
Research Discipline Cancer and Tumor Biology
Primary or Secondary Primary
Target Species Human
Form Prediluted
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.