Epredia™ Lab Vision™ Prostate Specific Membrane Antigen (PSMA) Rabbit Monoclonal Antibody, supernatant

Employ part of a comprehensive antibody portfolio with the Epredia™ Prostate Specific Membrane Antigen, Rabbit Monoclonal Antibody. Studies show rabbit monoclonal antibodies are more sensitive and specific than other available markers.

Supplier:  Epredia™ RM9131S0

Catalog No. RM9131S0

Description

Prostate Specific Membrane Antigen (PSMA) is a surface glycoprotein with restricted expression to normal prostate tissue, primary and metastatic prostate cancer and the neovasculature of various nonprostatic epithelial malignancies. Overexpression of PSMA is correlated with high tumor grade, non-diploid tumors, and advanced tumor stage. Even though PSA is useful in identifying the prostate origin of cancers, PSMA shows moderate to strong positivity in one-half of the cells per case that show relatively poor PSA staining, and is excellent in differentiating between prostatic adenocarcinoma and urothelial carcinoma. PSMA is expressed in 94.3% to 100% of primary and 57.7% to 100% of metastatic prostatic carcinomas. PSMA is recognized as a viable target for cancer therapy.

Host Species: Rabbit

Clone: SP29

Species Reactivity: Human. Others not known.

Immunogen: C-terminal

Molecular Weight: 84kDa

Positive Control: Prostate carcinoma

Cellular Localization: Cytoplasmic and membrane

Recommended for:

• Immunohistochemistry (Formalin/paraffin)

Specifications

• Antigen: Prostate Specific Membrane Antigen (PMSA)
• Classification: Monoclonal
• Conjugate: Unconjugated
• Immunogen: C-terminal
• Regulatory Status: IVD
• Primary or Secondary: Primary
• Form: Concentrated

• Applications: Immunohistochemistry (Paraffin)
• Clone: SP29
• Host Species: Rabbit
• Quantity: 100 μL
• Research Discipline: Cancer and Tumor Biology
• Target Species: Human
• Isotype: IgG