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  6. Epredia™ Lab Vision™ Raf-1 (Phospho-specific) Ab-2 Rat Monoclonal Antibody with BSA and azide

Epredia™ Lab Vision™ Raf-1 (Phospho-specific) Ab-2 Rat Monoclonal Antibody with BSA and azide

Catalog No. RT1732R1 Shop All Epredia Products
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Quantity:
1 mL
Form:
Prediluted
Concentration:
Prediluted
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RT1732R1 1 mL Prediluted Prediluted
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Catalog No. RT1732R1 Supplier Epredia™ Supplier No. RT1732R1

Description

Provide accurate, reproducible results with the Epredia™ Raf-1 (Phospho-specific) Ab-2, Rat Monoclonal Antibody.

Raf1 is an important mediator of signal transduction pathway. It is activated through activation by Src and protein kinase C. It further phosphorylates Mek1 and cdc25. It can bind to GTP-bound Ras through N-terminal domain. It also interacts with hsp90 and 14.3.3 family of proteins.

Host Species: Rat

Clone: pS338[DPR/2/2A/3A]

Isotype: IgG1

Species Reactivity: Human. Others not known.

Epitope: GQRDS™SYY™WEIEAS

Immunogen: A synthetic peptide corresponding to aa GQRDS™SYY™WEIEAS

Molecular Weight: 74kDa

Positive Control: Tonsil

Cellular Localization: Nuclear Ab-2 binds to phosphorylated serine residue at aa338. It does not bind to unactivated Raf-1 or Raf-1 phosphorylated at Y341 and S339.

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

Note:

USA: RUO; Int'l: RUO


General References:

1. Mason C S, et al. (1999) EMBO J, 18:2137-2148.

Specifications

Antigen Raf-1 (Phospho-specific) Ab-2
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone pS338[DPR/2/2A/3A]
Concentration Prediluted
Conjugate Unconjugated
Formulation Ready-to-use for IHC (UVLP)
Host Species Rat
Immunogen A synthetic peptide corresponding to aa GQRDSasteriskSYYasteriskWEIEAS
Quantity 1 mL
Regulatory Status RUO
Research Discipline Signal Transduction
Primary or Secondary Primary
Target Species Human
Form Prediluted
Isotype IgG1
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