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  6. Epredia™ Lab Vision™ Retinoblastoma (Rb) Ab-1 Mouse Monoclonal Antibody, 200μg/mL, biotinylated, BSA and azide

Epredia™ Lab Vision™ Retinoblastoma (Rb) Ab-1 Mouse Monoclonal Antibody, 200μg/mL, biotinylated, BSA and azide

Catalog No. MS107B0 Shop All Epredia Products
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Quantity:
100 μL
200 μL
500 μL
1 mL
7 mL
Conjugate:
Biotin
Unconjugated
Form:
Concentrated
Prediluted
Concentration:
1mg/mL
200μg/mL
Prediluted
9 product options available for selection
Product selection table with 9 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity Conjugate Form Concentration
MS107B0 100 μL Biotin Concentrated 200μg/mL
MS107P1ABX 100 μL Unconjugated Concentrated 1mg/mL
MS107P1 500 μL Unconjugated Concentrated 200μg/mL
MS107R7 7 mL Unconjugated Prediluted Prediluted
MS107B1 500 μL Biotin Concentrated 200μg/mL
MS107B 1 mL Biotin Concentrated 200μg/mL
MS107P0 100 μL Unconjugated Concentrated 200μg/mL
MS107PABX 200 μL Unconjugated Concentrated 1mg/mL
MS107R1 1 mL Unconjugated Prediluted Prediluted
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 9 options available.
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Catalog No. MS107B0 Supplier Epredia™ Supplier No. MS107B0

Description

Provide accurate, reproducible results with the Epredia™ Retinoblastoma (Rb) Ab-1, Mouse Monoclonal Antibody.

Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.

Host Species: Mouse

Clone: 1F8; same as Rb1

Isotype: IgG1

Species Reactivity: Human. Does not react with mouse and rat. Others not known.

Epitope: aa 703-722

Immunogen: Recombinant human Rb protein

Molecular Weight: 105kDa

Positive Control: Ls174T, HT29, HUVEC cells; Normal colon, Breast CA and colon CA

Cellular Localization: Nuclear Ab-1 specifically stains the nuclei of BT-20 cells and primary human foreskin fibroblast (HFF) cells. It reacts with hyperphosphorylated and un (under) phosphorylated form of Rb protein. It shows no cross reaction with p107 and p130.

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native and denatured)
  • Flow Cytometry

Note:

USA: RUO; Int'l: RUO

Specifications

Antigen Retinoblastoma (Rb) Ab-1
Applications Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 1F8; same as Rb1
Concentration 200μg/mL
Conjugate Biotin
Host Species Mouse
Immunogen Recombinant human Rb protein
Quantity 100 μL
Regulatory Status RUO
Research Discipline Cancer and Tumor Biology
Primary or Secondary Primary
Target Species Human
Form Concentrated
Isotype IgG1
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