TAG-72/CA 72-4TM Ab-1 Mouse Monoclonal Antibody, Epredia™

Provide accurate, reproducible results with the Epredia™ TAG-72/CA 72-4 Ab-1, Mouse Monoclonal Antibody.

Supplier:  Epredia MS138P0

Catalog No. MS138P0

Description

Tumor-associated glycoprotein (TAG-72) is an oncofetal antigen with properties of a mucin. About 60% of carcinoma patients express TAG-72 in their sera.

Host Species: Mouse

Clone: B72.3

Isotype: IgG1/κ

Species Reactivity: Human, Cow, Dog, Hamster and Rat. Others not known.

Epitope: Mucin-carried-sialylated-Tn epitope

Immunogen: Membrane-enriched fraction of a human breast carcinoma liver metastasis

Molecular Weight: >1000kDa

Positive Control: Breast or lung CA

Cellular Localization: Cell surface and cytoplasmic. The majority of human adenocarcinomas including colorectal, pancreatic, gastric, ovarian, endometrial, mammary, and non-small cell lung cancer display some cell populations that are positive for Ab-1 staining. Weak or no reactivity has been observed with most cell types of normal adult tissue excepting the secretory endometrium. Ab-1 is reportedly useful in distinguishing pulmonary adenocarcinomas (B72.3+) from pleural mesotheliomas (B72.3-).

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Flow Cytometry
• Radioimaging

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: TAG-72/CA 72-4 Ab-1
• Classification: Monoclonal
• Concentration: 200μg/mL
• Host Species: Mouse
• Quantity: 100 μL
• Research Discipline: Cancer and Tumor Biology
• Target Species: Bovine, Canine, Hamster, Human, Rat
• Isotype: IgG2a κ

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin)
• Clone: B72.3
• Conjugate: Unconjugated
• Immunogen: Membrane-enriched fraction of a human breast carcinoma liver metastasis
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Concentrated