TIMP-1 Ab-2 Mouse Monoclonal Antibody, Epredia™
Provide accurate, reproducible results with the Epredia™ TIMP-1 Ab-2, Mouse Monoclonal Antibody.
Manufacturer: Epredia MS608R7
DescriptionTissue inhibitor of metalloproteinases-1 (TIMP-1) and Tissue inhibitor of metalloproteinases-2 (TIMP-2) are inhibitory enzymes of matrix metalloproteinase family, and are thought to be of great importance in the maintenance of connective tissue integrity. TIMP-1 forms a complex of 1:1 stoichiometry with activated interstitial collagenase, activated stromelysin, active form of 72kDa Type IV collagenase (also known as MMP-2 or gelatinase A), and latent and active forms 92kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMPs inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
Host Species: Mouse
Species Reactivity: Human. Others not known.
Epitope: Not determined
Immunogen: Recombinant human TIMP-1
Molecular Weight: 28.5kDa
Positive Control: Conditioned, serum-free medium from (TPA-treated) human fetal lung cell line HFL-1; Bladder, breast and ovarian CA
Cellular Localization: Cytoplasmic
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
USA: RUO; Int'l: RUO
|Recombinant human TIMP-1|
|Immunohistochemistry (Paraffin), Western Blot|
|Proteases And Inhibitors|
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