TIMP-2 Ab-5 Mouse Monoclonal Antibody, Epredia™

Provide accurate, reproducible results with the Epredia™ TIMP-2 Ab-5, Mouse Monoclonal Antibody.

Supplier:  Epredia MS1485R7

Catalog No. MS1485R7

Description

TIMP-1 and TIMP-2 are inhibitory enzymes of matrix metalloproteinase family, and are thought to be of great importance in the maintenance of connective tissue integrity. TIMP-2 shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

Host Species: Mouse

Clone: 3A4

Isotype: IgG2a/κ

Species Reactivity: Human, Mouse, Rat, Rabbit, Cow and Guinea Ppig. Others not known.

Epitope: N-terminal

Immunogen: A synthetic peptide from the N-terminal region of human TIMP-2 protein

Molecular Weight: 21kDa

Positive Control: Conditioned, serum-free medium from (TPA-treated) HFL-1 cells; Pancreatic or colon CA

Cellular Localization: Cytoplasmic

Recommended for:

• Immunohistochemistry (Formalin/paraffin only)
• Western Blotting
• Immunoprecipitation (Not suitable)

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: TIMP-2 Ab-5
• Classification: Monoclonal
• Conjugate: Unconjugated
• Immunogen: A synthetic peptide from the N-terminal region of human TIMP-2 protein
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Prediluted

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: 3A4
• Host Species: Mouse
• Quantity: 7 mL
• Research Discipline: Proteases And Inhibitors
• Target Species: Bovine, Guinea Pig, Human, Mouse, Rabbit, Rat
• Isotype: IgG2a κ