TIMP-2 Ab-5 Mouse Monoclonal Antibody, Epredia™
Provide accurate, reproducible results with the Epredia™ TIMP-2 Ab-5, Mouse Monoclonal Antibody.
Manufacturer: Epredia MS1485R7
DescriptionTIMP-1 and TIMP-2 are inhibitory enzymes of matrix metalloproteinase family, and are thought to be of great importance in the maintenance of connective tissue integrity. TIMP-2 shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
Host Species: Mouse
Species Reactivity: Human, Mouse, Rat, Rabbit, Cow and Guinea Ppig. Others not known.
Immunogen: A synthetic peptide from the N-terminal region of human TIMP-2 protein
Molecular Weight: 21kDa
Positive Control: Conditioned, serum-free medium from (TPA-treated) HFL-1 cells; Pancreatic or colon CA
Cellular Localization: Cytoplasmic
- Immunohistochemistry (Formalin/paraffin only)
- Western Blotting
- Immunoprecipitation (Not suitable)
USA: RUO; Int'l: RUO
|A synthetic peptide from the N-terminal region of human TIMP-2 protein|
|Immunohistochemistry (Paraffin), Western Blot|
|Proteases And Inhibitors|
|Bovine, Guinea Pig, Human, Mouse, Rabbit, Rat|
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