Transforming Growth Factor α (TGFα) Ab-1 Mouse Monoclonal Antibody, Epredia™

Epredia™ Transforming Growth Factor α (TGFα) Ab-1, Mouse Monoclonal Antibody provides accurate, reproducible results.

Supplier:  Epredia MS670P

Catalog No. MS670P

Description

TGFα (aa 50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.

Host Species: Mouse

Clone: MF9

Isotype: IgG1/κ

Species Reactivity: Human, Cow, Rat and Mouse. Others not known.

Epitope: C-terminal

Immunogen: A 17-amino acid synthetic peptide from the carboxyl-terminus of rat TGFα

Molecular Weight: 6kDa

Positive Control: Recombinant TGFα protein, A2058 cells

Cellular Localization: Cytoplasmic Ab-1 shows no cross-reaction with EGF and the neuropeptide synenkephalin. Ab-1 is excellent for staining of formalin-fixed, paraffin-embedded tissues. The staining with Ab-1 is completely blocked by the peptide used for raising this antibody.

Recommended for:

• Western Blotting

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: Transforming Growth Factor alpha (TGFalpha) Ab-1
• Classification: Monoclonal
• Concentration: 200μg/mL
• Host Species: Mouse
• Quantity: 1 mL
• Research Discipline: Signal Transduction
• Target Species: Bovine, Human, Mouse, Rat
• Isotype: IgG2a κ

• Applications: Western Blot
• Clone: MF9
• Conjugate: Unconjugated
• Immunogen: A 17-amino acid synthetic peptide from the carboxyl-terminus of Rat TGFalpha
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Concentrated