Transglutaminase II Ab-1 Mouse Monoclonal Antibody, Epredia™
Epredia™ Transglutaminase II Ab-1, Mouse Monoclonal Antibody provides accurate, reproducible results.
Manufacturer: Epredia MS224B1
DescriptionTransglutaminase II catalyzes calcium-dependent post-translational modification of proteins by formation of an isopeptide bond within or between polypeptide chains. It is also known as TGC, tTG, type II-, Gh, cytosolic-, liver-, endothelial-, erythrocyte-, cellular-transglutaminase. Different tissues and cell types express varying amounts of tissue transglutaminase with a markedly hugh expression in rheumatoid lesions. It is implicated in programmed cell death, signal transduction, drug-resistance, cell growth, endocytosis, insulin secretion, cell adhesion, cataract formation, and wound healing.
Host Species: Mouse
Clone: CUB 7402
Species Reactivity: Human, Dog, Rabbit and Guinea Pig. Does not react with mouse and rat. Others not known.
Epitope: aa 447-478
Immunogen: Purified guinea pig liver TGase II
Molecular Weight: 77-85kDa
Positive Control: HUVEC cells, Breast CA
Cellular Localization: Cytoplasm, membrane and extracellular matrix Ab-1 inhibits the TGase II activity.
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunoprecipitation (Native and denatured)
- Affinity Purification
- Biological Blockade
USA: RUO; Int'l: RUO
|Transglutaminase II Ab-1|
|Canine, Guinea Pig, Human, Rabbit|
|Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot|
|Purified guinea pig liver TGase II|
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