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Tubulin-α Ab-2 Mouse Monoclonal Antibody, Epredia™

Catalog No. MS581P0 Shop All Epredia Products
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Quantity:
100 μL
200 μL
500 μL
1 mL
7 mL
Form:
Concentrated
Prediluted
Concentration:
1mg/mL
200μg/mL
Prediluted
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Catalog No. Quantity Form Concentration
MS581P0 100 μL Concentrated 200μg/mL
MS581PABX 200 μL Concentrated 1mg/mL
MS581P1 500 μL Concentrated 200μg/mL
MS581P 1 mL Concentrated 200μg/mL
MS581P1ABX 100 μL Concentrated 1mg/mL
MS581R1 1 mL Prediluted Prediluted
MS581R7 7 mL Prediluted Prediluted
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Catalog No. MS581P0 Supplier Epredia Supplier No. MS581P0

Description

Provide accurate, reproducible results with the Epredia™ Tubulin-α Ab-2, Mouse Monoclonal Antibody.

Microtubules, the major cytoskeletal elements found in all eukaryotic cells, consist of Tubulin, which is a dimer of two 55kDa subunits: α and Β. Microtubules play key roles in chromosome segregation in mitosis, intracellular transport, ciliary and flagellar bending, and structural support of the cytoskeleton.

Host Species: Mouse

Clone: DM1A

Isotype: IgG1/κ

Species Reactivity: Human, Cow, Pig, Rat, Mouse, Guinea Pig, Gerbil, Frog and Chicken. Others not known.

Epitope: aa 426-450

Immunogen: Native chick brain microtubules

Molecular Weight: 57kDa

Positive Control: Ls174T, MAD109 cells; skin or lung

Cellular Localization: Cytoplasmic Ab-2 causes the 10nm filaments to collapse into large lateral aggregates collecting in the cell periphery or tight juxtanuclear caps. It does not block microtubule assembly. It does not inhibit polymerization or depolymerization of platelet tubulin in vitro. It blocks (by 70-80%) the ability of tubulin dimers (with GppNHp bound) to promote a stable inhibition of adenylyl cyclase.

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native and denatured)
  • Electron Microscopy

Note:

USA: RUO; Int'l: RUO

Specifications

Antigen Tubulin, alpha Ab-2
Applications Immunoassay, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Monoclonal
Clone DM1A
Concentration 200μg/mL
Conjugate Unconjugated
Host Species Mouse
Immunogen Native chick brain microtubules
Quantity 100 μL
Regulatory Status RUO
Research Discipline Cytoskeletal Protein
Primary or Secondary Primary
Target Species Bovine, Chicken, Frog, Gerbil, Guinea Pig, Human, Mouse, Pig, Rat
Form Concentrated
Isotype IgG2a κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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