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  6. Epredia™ Lab Vision™ XPA Ab-1 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide

Epredia™ Lab Vision™ XPA Ab-1 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide

Catalog No. MS650R1 Shop All Epredia Products
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Quantity:
1 mL
Form:
Prediluted
Concentration:
Prediluted
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Catalog No. Quantity Form Concentration
MS650R1 1 mL Prediluted Prediluted
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Catalog No. MS650R1 Supplier Epredia™ Supplier No. MS650R1

Description

Provide accurate, reproducible results with the Epredia™ XPA Ab-1, Mouse Monoclonal Antibody.

The XPA (xeroderma pigmentosum group A) protein specifically recognizes the UV-or chemically damaged DNA lesions, and triggers the nucleotide excision repair process. XPA binds to the replication protein A (RPA) or the excision repair cross complementing 1 protein (ERCC1). In the absence of nucleotide excision repair persisting (unrepaired) DNA lesions (adducts) may lead to the accumulation of gene mutations and ultimately to cancer. Xeroderma pigmentosum patients have a > 2000 fold increased risk to develop skin cancer at sun-exposed areas.

Host Species: Mouse

Clone: 12F5

Isotype: IgG2a/k

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Recombinant human XPA protein

Molecular Weight: ∽40kDa

Positive Control: Ls174T or MCF-7 cells or human tonsil

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting

Note:

USA: RUO; Int'l: RUO

Specifications

Antigen XPA Ab-1
Applications Western Blot
Classification Monoclonal
Clone 12F5
Concentration Prediluted
Conjugate Unconjugated
Formulation Ready-to-use for IHC (UVLP)
Host Species Mouse
Immunogen Recombinant human XPA protein
Quantity 1 mL
Regulatory Status RUO
Research Discipline DNA Repair
Primary or Secondary Primary
Target Species Human
Form Prediluted
Isotype IgG2a κ
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