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  6. Epredia™ Lab Vision™ XPF Ab-1 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide

Epredia™ Lab Vision™ XPF Ab-1 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide

Catalog No. MS1381R1 Shop All Epredia Products
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Quantity:
1 mL
Form:
Prediluted
Concentration:
Prediluted
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Catalog No. Quantity Form Concentration
MS1381R1 1 mL Prediluted Prediluted
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Catalog No. MS1381R1 Supplier Epredia™ Supplier No. MS1381R1

Description

Provide accurate, reproducible results with the Epredia™ XPF Ab-1, Mouse Monoclonal Antibody.

The structure-specific ERCC1/XPF endonuclease complex is implicated in the repair of two distinct types of lesions in DNA: NER for UV-induced lesions and bulky chemical adducts; and recombination repair of the very genotoxic interstrand cross-links. NER mechanism involves dual incisions on both sides of the damage catalyzed by two nucleases. In mammalian cells XPG cleaves 3' of the DNA lesion while the ERCC1-XPF complex makes the 5' incision.

Host Species: Mouse

Clone: 219

Isotype: IgG2/κ

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Recombinant human XPF protein

Molecular Weight: ∽110kDa

Positive Control: MCF-7 cells or human tonsil

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting

Note:

USA: RUO; Int'l: RUO

Specifications

Antigen XPF Ab-1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 219
Concentration Prediluted
Conjugate Unconjugated
Formulation Ready-to-use for IHC (UVLP)
Host Species Mouse
Immunogen Recombinant human XPF protein
Quantity 1 mL
Regulatory Status RUO
Research Discipline DNA Repair
Primary or Secondary Primary
Target Species Human
Form Prediluted
Isotype IgG2
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