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  6. Epredia™ Lab Vision™ XRCC1 (X-Ray Repair Cross Complementing Protein 1) Ab-3 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide

Epredia™ Lab Vision™ XRCC1 (X-Ray Repair Cross Complementing Protein 1) Ab-3 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide

Catalog No. MS1393R1 Shop All Epredia Products
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Quantity:
1 mL
Form:
Ready-to-Use
Concentration:
Prediluted
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Catalog No. Quantity Form Concentration
MS1393R1 1 mL Ready-to-Use Prediluted
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Catalog No. MS1393R1 Supplier Epredia™ Supplier No. MS1393R1

Description

Provide accurate, reproducible results with the Epredia™ XRCC1 (X-Ray Repair Cross Complementing Protein 1) Ab-3, Mouse Monoclonal Antibody.

X-Ray Repair Cross Complementing (XRCC1) plays a role in excision repair of DNA after ionizing irradiation. XRCC1 binds to DNA ligase III through the C-terminal 96 amino acids and to DNA polymerase β through the N-terminal half. In testis XRCC1 is expressed at high levels. Cells with a mutation of this gene exhibit decreased single strand break repair and reduced recombination repair. They show increased double strand breaks, and sister chromatid exchange is increased up to 10-fold. The XRCC1 might serve as a scaffold protein during base excision-repair.

Host Species: Mouse

Clone: 144

Isotype: IgG2a/κ

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Recombinant human XRCC1 protein

Molecular Weight: 85kDa

Positive Control: Ls174T, or HeLa cells; normal testis

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Denatured verified)

Note:

USA: RUO; Int'l: RUO



Specifications

Antigen XRCC1 (X-Ray Repair Cross Complementing Protein1) Ab-3
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 144
Concentration Prediluted
Conjugate Unconjugated
Formulation Ready-to-use for IHC (UVLP)
Host Species Mouse
Immunogen Recombinant human XRCC1 protein
Quantity 1 mL
Regulatory Status RUO
Research Discipline DNA Repair
Primary or Secondary Primary
Target Species Human
Form Ready-to-Use
Isotype IgG2a κ
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