Invitrogen™ LACC1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA569915

Catalog No. PIPA569915

Description

This target displays homology in the following species: Cow: 86%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 92%.

This gene encodes an oxidoreductase that promotes fatty-acid oxidation, with concomitant inflammasome activation, mitochondrial and NADPH-oxidase-dependent reactive oxygen species production, and bactericidal activity of macrophages. The encoded protein forms a complex with fatty acid synthase on peroxisomes and is thought to be modulated by peroxisome proliferator-activated receptor signaling events. Naturally occurring mutations in this gene are associated with inflammatory bowel disease, Behcet's disease, leprosy, ulcerative colitis, early-onset Crohn's disease, and systemic juvenile idiopathic arthritis.

Specifications

• Antigen: LACC1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LACC1
• Gene Alias: 9030625A04Rik; C12H13orf31; C13orf31; FAMIN; Fatty acid metabolism-immunity nexus; LACC1; laccase (multicopper oxidoreductase) domain containing 1; laccase domain containing 1; laccase domain-containing protein 1; purine nucleoside phosphorylase LACC1; laccase domain-containing protein 1; RGD1310185; si:ch211-187f22.1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 210808
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q8BZT9
• Gene Symbols: LACC1
• Immunogen: synthetic peptide directed towards the middle region of human LACC1 (aa 381-430).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov