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LAG3 Recombinant Rabbit Monoclonal Antibody (BLR028F), Bethyl Laboratories

Rabbit Recombit Monoclonal Antibody

Supplier:  Bethyl Laboratories, Inc A700028

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Catalog No. 50-157-2649


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Description

Description

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For ICC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections. For IHC, epitope retrieval with citrate buffer pH 6.0 is recommende

LAG-3 is a 70-kDa surface glycoprotein belonging to the Ig superfamily with homology to CD4. LAG-3 binds to MHC class II with higher affinity than CD4 and is thought to be involved in the negative regulation of T cell activation and homeostatic proliferation. Surface expression of LAG-3 has been reported on activated T cells (including regulatory T cells) and NK cells. CD8+ T cells usually express LAG-3 at significantly higher levels than CD4+ T cells. Coexpression of LAG-3 and CD49b has been proposed to identify human and mouse Type 1 regulatory T cells (Tr1 cells).
Specifications

Specifications

LAG3
Recombinant Monoclonal
Unconjugated
LAG3
Lymphocyte-activation gene 3, CD223
Rabbit
Antigen affinity chromatography
RUO
3902
4° C
Liquid
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
BLR028F
BBS with 0.09% sodium azide; pH 8.2
P18627
LAG3
recombit protein representing the extracellular domain of human LAG3
100 μL
Primary
Human
Antibody
IgG
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