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LAG3 Recombinant Rabbit Monoclonal Antibody (BLR028F), Bethyl Laboratories
Rabbit Recombit Monoclonal Antibody
Supplier: Bethyl Laboratories, Inc A700028

Description
The recommended shelf life for this product is 1 year from date of receipt. Application Note: For ICC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections. For IHC, epitope retrieval with citrate buffer pH 6.0 is recommende
LAG-3 is a 70-kDa surface glycoprotein belonging to the Ig superfamily with homology to CD4. LAG-3 binds to MHC class II with higher affinity than CD4 and is thought to be involved in the negative regulation of T cell activation and homeostatic proliferation. Surface expression of LAG-3 has been reported on activated T cells (including regulatory T cells) and NK cells. CD8+ T cells usually express LAG-3 at significantly higher levels than CD4+ T cells. Coexpression of LAG-3 and CD49b has been proposed to identify human and mouse Type 1 regulatory T cells (Tr1 cells).Specifications
LAG3 | |
Recombinant Monoclonal | |
Unconjugated | |
LAG3 | |
Lymphocyte-activation gene 3, CD223 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
3902 | |
4° C | |
Liquid |
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot | |
BLR028F | |
BBS with 0.09% sodium azide; pH 8.2 | |
P18627 | |
LAG3 | |
recombit protein representing the extracellular domain of human LAG3 | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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