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LAG3 Recombinant Rabbit Monoclonal Antibody (BLR028F), Bethyl Laboratories

Catalog No. 501572650
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100 μL
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Catalog No. Quantity
50-157-2650 10 μL
50-157-2649 100 μL
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Catalog No. 50-157-2650 Supplier Bethyl Laboratories, Inc Supplier No. A700028T
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Description

Rabbit Recombit Monoclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For ICC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections. For IHC, epitope retrieval with citrate buffer pH 6.0 is recommende

LAG-3 is a 70-kDa surface glycoprotein belonging to the Ig superfamily with homology to CD4. LAG-3 binds to MHC class II with higher affinity than CD4 and is thought to be involved in the negative regulation of T cell activation and homeostatic proliferation. Surface expression of LAG-3 has been reported on activated T cells (including regulatory T cells) and NK cells. CD8+ T cells usually express LAG-3 at significantly higher levels than CD4+ T cells. Coexpression of LAG-3 and CD49b has been proposed to identify human and mouse Type 1 regulatory T cells (Tr1 cells).

Specifications

Antigen LAG3
Applications Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Recombinant Monoclonal
Clone BLR028F
Conjugate Unconjugated
Formulation BBS with 0.09% sodium azide; pH 8.2
Gene LAG3
Gene Accession No. P18627
Gene Alias Lymphocyte-activation gene 3, CD223
Gene Symbols LAG3
Host Species Rabbit
Immunogen recombit protein representing the extracellular domain of human LAG3
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3902
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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