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Lambda Light Chain Antibody (ICO-106), Novus Biologicals™
SDP

Catalog No. NBP22946202 Shop All R&D Systems Products
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0.2 mg
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NBP22946202 0.2 mg
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Catalog No. NBP22946202 Supplier Novus Biologicals Supplier No. NBP2294620.2MG

Specifications

Antigen Lambda Light Chain
Applications Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation
Classification Monoclonal
Clone ICO106
Concentration 0.2mg/mL
Conjugate Unconjugated
Dilution Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, ELISA 1-5ug/ml for coating, Immunohistochemistry 0.5-1ug/ml, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml, SDS-Page
Formulation PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Alias IGLC, immunoglobulin lambda constant group
Gene Symbols IGLC2
Host Species Mouse
Immunogen Human IgG was used as immunogen to generate the Lambda antibody.
Molecular Weight of Antigen 22.5 kDa
Purification Method Protein G purified
Quantity 0.2 mg
Regulatory Status RUO
Research Discipline Adaptive Immunity, Immunology
Primary or Secondary Primary
Gene ID (Entrez) 3536
Test Specificity This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Target Species Human
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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