Invitrogen™ Lambda light chain Monoclonal Antibody (A8G3)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA544936

Catalog No. PIMA544936

Description

Lambda light chain Monoclonal Antibody for Western Blot, ICC/IF, IHC (P), Flow

Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five types) and two light chains (kappa, lambda; both having a molecular weight of 22.5 kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30. Antibodies to the kappa light chain are reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.

Specifications

• Antigen: Lambda light chain
• Classification: Monoclonal
• Concentration: 2 mg/mL
• Formulation: PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P01701, P0CG04
• Gene Symbols: IGL, IGLC1, IGLV, IGLV1-51
• Immunogen: Constant region of natural protein (constant region of light chain lambda chain).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: A8G3
• Conjugate: Unconjugated
• Gene: IGLC1
• Gene Alias: Bence Jones Protein; BJP; Clambda1; Ig lambda chain V-I region BL2; IgL; Igl@; IGLC; IGLC 1/2/3; IGLC1; Igl-C1; IGLL5; IGLV; IGLV@; immmunoglobulin lambda light chain variable region; Immunoglobulin L; immunoglobulin lambda chain complex; immunoglobulin lambda constant 1; immunoglobulin lambda constant 7; immunoglobulin lambda light chain; immunoglobulin lambda light chain constant region; immunoglobulin lambda light chain V-J region; immunoglobulin lambda variable cluster; Lambda LC; lambda-immunoglobulin; LOC100060608; Mcg Marker; Paraprotein
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 28820, 3535, 3537, 3546
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid