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Lamin A/C Monoclonal Antibody (3A6-4C11), Active Motif™
SDP

Catalog No. 502277232
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50 μL
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50-227-7232 50 μL
50-199-3990 10 μg
50-199-3989 100 μg
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Catalog No. 50-227-7232 Supplier Active Motif Supplier No. 39087
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Mouse Monoclonal Antibody

Lamins are a class of intermediate filament proteins that form a matrix on the inner surface of the nuclear envelope. These proteins are found in many different cell types in three different forms (A, B, and C). Lamins A and C are alternatively spliced versions of the LMNA gene. The LMNA gene has been linked to many disorders of the muscular system, nervous system, and the fat distributions systems including: Emery-Dreifuss muscular dystrophy, Dunnigan-type familial partial lipodystrophy (FPLD), limb-girdle muscular dystrophy (LGMD1B), dilated cardiomyopathy (CMD1A), axonal neuropathy (Charcot-Marie-Tooth disease; CMT2B1), and mandibuloacral dysplasia (MAD).

Specifications

Antigen Lamin A/C
Applications Western Blot, Immunofluorescence, Immunocytochemistry
Classification Monoclonal
Clone 3A6-4C11
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation antibody with 30% glycerol and 0.035% sodium azide; pH
Gene LMNA
Gene Accession No. P02545, P48678, P48679
Gene Alias 70 kDa lamin; BOS_2775; CDCD1; CDDC; CMD1A; CMT2B1; Dhe; EMD2; FPL; FPLD; FPLD2; HGPS; I79_009616; IDC; lamin; lamin A; lamin A/C; lamin A/C-like 1; Lamin A+C mutant; Lamin AC; lamin C; lamin C2; Lamin-A/C; LDP1; LFP; LGMD1B; LMN1; LMNA; LMNC; LMNL1; mutant 453W; Mutant lamin A/C; Prelamin-A/C; PRO1; progerin mutant; Renal carcinoma antigen NY-REN-32; RP11-54H19.1
Gene Symbols LMNA
Host Species Mouse
Immunogen This Lamin A/C antibody was raised against a recombinant protein corresponding to amino acids 430-545 of human Lamin A.
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100757316, 16905, 4000, 60374
Target Species Monkey, Rat, Human, Hamster, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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