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Invitrogen™ Lamin A/C Monoclonal Antibody (4E7)
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Catalog No. PIMA515882
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100 μL
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PIMA515882 100 μL
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Catalog No. PIMA515882 Supplier Invitrogen™ Supplier No. MA515882
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Description

Mouse Monoclonal Antibody

MA5-15882 targets LMNA in indirect ELISA, IHC and WB applications and shows reactivity with Human, mouse, and Rat samples. The MA5-15882 immunogen is purified recombinant fragment of human LMNA expressed in E. Coli. MA5-15882 detects LMNA which has a predicted molecular weight of approximately 74kDa.

Lamins are a class of intermediate filament proteins that form a matrix on the inner surface of the nuclear envelope. These proteins are found in many different cell types in three different forms (A, B, and C). Lamins A and C are alternatively spliced versions of the LMNA gene. The LMNA gene has been linked to many disorders of the muscular system, nervous system, and the fat distributions systems including: Emery-Dreifuss muscular dystrophy, Dunnigan-type familial partial lipodystrophy (FPLD), limb-girdle muscular dystrophy (LGMD1B), dilated cardiomyopathy (CMD1A), axonal neuropathy (Charcot-Marie-Tooth disease; CMT2B1), and mandibuloacral dysplasia (MAD).
TRUSTED_SUSTAINABILITY

Specifications

Antigen Lamin A/C
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 4E7
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Ascites with 0.03% sodium azide
Gene LMNA
Gene Accession No. P02545, P48678, P48679
Gene Alias 70 kDa lamin; cb948; CDCD1; CDDC; CMD1A; CMT2B1; Dhe; EMD2; FPL; FPLD; FPLD2; HGPS; I79_009616; IDC; lamin; lamin A; lamin A/C; lamin A/C L homeolog; lamin A/C-like 1; Lamin A+C mutant; Lamin AC; lamin a-c; lamin C; lamin C2; lamin-A; Lamin-A/C; LDP1; LFP; LGMD1B; LMN1; lmna; LMNA protein; lmna.L; lmna-A; LMNC; LMNL1; mutant 453W; Mutant lamin A/C; nuclear intermediate filament protein; nuclear lamin A; prelamin-A/C; PRO1; progerin mutant; Renal carcinoma antigen NY-REN-32; RP11-54H19.1; unnamed protein product; wu:fk66d12; XELAEV_18040808mg
Gene Symbols LMNA
Host Species Mouse
Immunogen Purified recombinant fragment of human LMNA expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16905, 4000, 60374
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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