Invitrogen™ Lamin A/C Recombinant Rabbit Monoclonal Antibody (4L8Q0)

Catalog No.	Quantity
PIMA535284	100 μL

Catalog No. PIMA535284

Supplier: Invitrogen™ MA535284

Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: SSHSSQTQGG GSVTKKRKLE STESRSSFSQ HARTSGRVAV EEVDEEGKFV RLRNKSNEDQ SMGNWQIKRQ NGDDPLLTYR FPPKFTLKAG QVVTIWAAGA GATHSPPTDL VWKAQNTWGC GNSLRTALIN STGEEVAMRK LVRSVTVVED DEDEDGDDLL HHHHGSHCSS.

Lamins are a class of intermediate filament proteins that form a matrix on the inner surface of the nuclear envelope. These proteins are found in many different cell types in three different forms (A, B, and C). Lamins A and C are alternatively spliced versions of the LMNA gene. The LMNA gene has been linked to many disorders of the muscular system, nervous system, and the fat distributions systems including: Emery-Dreifuss muscular dystrophy, Dunnigan-type familial partial lipodystrophy (FPLD), limb-girdle muscular dystrophy (LGMD1B), dilated cardiomyopathy (CMD1A), axonal neuropathy (Charcot-Marie-Tooth disease; CMT2B1), and mandibuloacral dysplasia (MAD).

Specifications

• Antigen: Lamin A/C
• Applications: ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Classification: Recombinant Monoclonal
• Clone: 4L8Q0
• Concentration: 0.24 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene: LMNA
• Gene Accession No.: P02545, P48678, P48679
• Gene Alias: 70 kDa lamin; cb948; CDCD1; CDDC; CMD1A; CMT2B1; Dhe; EMD2; FPL; FPLD; FPLD2; HGPS; I79_009616; IDC; lamin; lamin A; lamin A/C; lamin A/C L homeolog; lamin A/C-like 1; Lamin A+C mutant; Lamin AC; lamin a-c; lamin C; lamin C2; lamin-A; Lamin-A/C; LDP1; LFP; LGMD1B; LMN1; lmna; LMNA protein; lmna.L; lmna-A; LMNC; LMNL1; mutant 453W; Mutant lamin A/C; nuclear intermediate filament protein; nuclear lamin A; prelamin-A/C; PRO1; progerin mutant; Renal carcinoma antigen NY-REN-32; RP11-54H19.1; unnamed protein product; wu:fk66d12; XELAEV_18040808mg
• Gene Symbols: LMNA
• Host Species: Rabbit
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 403-572 of human Lamin A/C (NP_7338211).
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 16905, 4000, 60374
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG