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Invitrogen™ Lamin A/C Monoclonal Antibody (GT9712)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA531474
Description
Keep as concentrated solution. Predicted reactivity: Mouse (87%), Rat (92%), Dog (96%), Pig (96%), Rhesus Monkey (99%), Chimpanzee (100%). Positive Control: HeLa, HeLa nuclear. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Lamins are a class of intermediate filament proteins that form a matrix on the inner surface of the nuclear envelope. These proteins are found in many different cell types in three different forms (A, B, and C). Lamins A and C are alternatively spliced versions of the LMNA gene. The LMNA gene has been linked to many disorders of the muscular system, nervous system, and the fat distributions systems including: Emery-Dreifuss muscular dystrophy, Dunnigan-type familial partial lipodystrophy (FPLD), limb-girdle muscular dystrophy (LGMD1B), dilated cardiomyopathy (CMD1A), axonal neuropathy (Charcot-Marie-Tooth disease; CMT2B1), and mandibuloacral dysplasia (MAD).
Specifications
Lamin A/C | |
Monoclonal | |
1 mg/mL | |
PBS with no preservative | |
P02545 | |
LMNA | |
Recombinant protein encompassing a sequence within the center region of human Lamin A/C. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG2b |
Immunoprecipitation, Western Blot, Immunocytochemistry | |
GT9712 | |
Unconjugated | |
LMNA | |
70 kDa lamin; cb948; CDCD1; CDDC; CMD1A; CMT2B1; Dhe; EMD2; FPL; FPLD; FPLD2; HGPS; I79_009616; IDC; lamin; lamin A; lamin A/C; lamin A/C L homeolog; lamin A/C-like 1; Lamin A+C mutant; Lamin AC; lamin a-c; lamin C; lamin C2; lamin-A; Lamin-A/C; LDP1; LFP; LGMD1B; LMN1; lmna; LMNA protein; lmna.L; lmna-A; LMNC; LMNL1; mutant 453W; Mutant lamin A/C; nuclear intermediate filament protein; nuclear lamin A; prelamin-A/C; PRO1; progerin mutant; Renal carcinoma antigen NY-REN-32; RP11-54H19.1; unnamed protein product; wu:fk66d12; XELAEV_18040808mg | |
Mouse | |
Protein G | |
RUO | |
4000 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
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