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Lamin-A Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501565124
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20 μL; Unconjugated
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Catalog No.
50-156-5124 20 μL; Unconjugated
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Catalog No. 50-156-5124 Supplier Bethyl Laboratories, Inc Supplier No. A303433AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections. Based on 100% sequence identity, this antibody is predicted to react with Rat and Pig

Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Required for normal development of peripheral nervous system and skeletal muscle and for muscle satellite cell proliferation. Required for osteoblastogenesis and bone formation. Also prevents fat infiltration of muscle and bone marrow, helping to maintain the volume and strength of skeletal muscle and bone.

Specifications

Antigen Lamin-A
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene LMNA
Gene Accession No. P02545, P48678
Gene Alias 70 kDa lamin, cardiomyopathy, dilated 1A (autosomal domit), CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, lamin A/C-like 1, LDP1, LFP, LGMD1B, limb girdle muscular dystrophy 1B (autosomal domit), LMN1, LMNC, LMNL1, prelamin-A/C, PRO1, progeria 1 (Hutchinson-Gilford type), renal carcinoma antigen NY-REN-32
Gene Symbols Lmna
Host Species Rabbit
Immunogen Between 550 and 600
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16905, 4000
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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