Invitrogen™ Lamin B Receptor Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA562061

Catalog No. PIPA562061

Description

Immunogen sequence: MPSRKFADGE VVRGRWPGSS LYYEVEILSH DSTSQLYTVK YKDGTELELK ENDIKPLTSF RQRKGGSTSS S Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 89%.

The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.

Specifications

• Antigen: Lamin B Receptor
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LBR
• Gene Alias: 3-beta-hydroxysterol Delta (14)-reductase; AI505894; C-14 sterol reductase; C14SR; Delta(14)-sterol reductase LBR; delta(14)-sterol reductase LBR; lamin-B receptor; Delta-14-SR; DHCR14B; FLJ43126; ic; ichthyosis; integral nuclear envelope inner membrane protein; lamin B receptor; lamin-B receptor; lamin-b receptor-like protein; Lbr; LMN2R; MGC9041; NBP60; PHA; PRO0650; sb:cb406; Sterol C14-reductase; TDRD18; tudor domain containing 18; wu:fb75h08; wu:fc47b04; wu:fd36b07; zgc:86649
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3930
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q14739
• Gene Symbols: LBR
• Immunogen: Recombinant protein corresponding to Human Lamin B Receptor. Recombinant protein control fragment (Product #RP-99796).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov