Invitrogen™ Lamin B Receptor Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5102777

Catalog No. PIPA5102777

Description

Antibody detects endogenous levels of total LBR.

The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.

Specifications

• Antigen: Lamin B Receptor
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LBR
• Gene Alias: 3-beta-hydroxysterol Delta (14)-reductase; AI505894; C-14 sterol reductase; C14SR; Delta(14)-sterol reductase LBR; delta(14)-sterol reductase LBR; lamin-B receptor; Delta-14-SR; DHCR14B; FLJ43126; ic; ichthyosis; integral nuclear envelope inner membrane protein; lamin B receptor; lamin-B receptor; lamin-b receptor-like protein; Lbr; LMN2R; MGC9041; NBP60; PHA; PRO0650; sb:cb406; Sterol C14-reductase; TDRD18; tudor domain containing 18; wu:fb75h08; wu:fc47b04; wu:fd36b07; zgc:86649
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3930, 98386
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q14739, Q3U9G9
• Gene Symbols: LBR
• Immunogen: A synthesized peptide derived from human LBR(Accession Q14739), corresponding to amino acid residues A332-D382.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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