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Invitrogen™ Laminin alpha-2 Monoclonal Antibody (CL3450)
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Catalog No. PIMA524656
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100 μL
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Catalog No. Quantity
PIMA524656 100 μL
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Catalog No. PIMA524656 Supplier Invitrogen™ Supplier No. MA524656
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Description

Mouse Monoclonal Antibody

Immunogen sequence: DKLKPIKELE DNLKKNISEI KELINQARKQ ANSIKVSVSS GGDCIRTYKP EIKKGSYNNI VVNVKTAVAD NLLFYLGSAK FIDFLAIEMR KGKVSFLWDV GSGVGRVEYP DLTIDDSYWY RIVASRTGRN GT Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 98%. Binds to an epitope located within the peptide sequence DKLKPIKELEDNLKK as determined by overlapping synthetic peptides.

Laminin is a non-collagenous protein of basement membranes. By rotary shadowing it has a cross-like shape, consisting of one long arm, (400 kD) and three short arms (200 kD). Antibodies to laminin localize exclusively in basement membranes. Laminin is found throughout the basement membrane, but the reaction with the antibodies to laminin is more intense in the lamina lucida, the part of the basement membrane adjacent to the cell membrane. Laminin binds to type IV collagen, a component exclusively localized in the basement membrane. Laminin has been shown to play a role in cell adhesion and attachment in vivo and in vitro.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Laminin alpha-2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone CL3450
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Lama2
Gene Accession No. P24043, Q60675
Gene Alias 5830440B04; dy; dystrophia muscularis; Lama2; laminin alpha-2; laminin M; Laminin M chain; laminin subunit alpha 2; laminin subunit alpha-2; laminin, alpha 2; laminin-12 subunit alpha; Laminin-2 subunit alpha; laminin-4 subunit alpha; LAMM; mer; merosin; Merosin heavy chain; mKIAA4087
Gene Symbols Lama2
Host Species Mouse
Immunogen Recombinant protein fragment of Human LAMA2 (Product #RP-108166)
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16773, 309368, 3908
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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