Invitrogen™ Laminin alpha-2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA549929

Catalog No. PA549929

Description

The antibody detects endogenous levels of total Laminin alpha-2 protein.

Laminin is a non-collagenous protein of basement membranes. By rotary shadowing it has a cross-like shape, consisting of one long arm, (400 kD) and three short arms (200 kD). Antibodies to laminin localize exclusively in basement membranes. Laminin is found throughout the basement membrane, but the reaction with the antibodies to laminin is more intense in the lamina lucida, the part of the basement membrane adjacent to the cell membrane. Laminin binds to type IV collagen, a component exclusively localized in the basement membrane. Laminin has been shown to play a role in cell adhesion and attachment in vivo and in vitro.

Specifications

• Antigen: Laminin alpha-2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Lama2
• Gene Alias: 5830440B04; dy; dystrophia muscularis; Lama2; laminin alpha-2; laminin M; Laminin M chain; laminin subunit alpha 2; laminin subunit alpha-2; laminin, alpha 2; laminin-12 subunit alpha; Laminin-2 subunit alpha; laminin-4 subunit alpha; LAMM; mer; merosin; Merosin heavy chain; mKIAA4087
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16773, 3908
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P24043, Q60675
• Gene Symbols: Lama2
• Immunogen: Synthesized peptide derived from internal of human LAMA2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG