Invitrogen™ Laminin alpha-5 Monoclonal Antibody (2D8/33)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA183286

Catalog No. PIMA183286

Description

This antibody does not react with mouse or rat. Mouse anti Human Laminin Alpha 5 antibody, clone 4C7 recognizes the laminin alpha 5 chain also known as Laminin-10 subunit alpha, Laminin-11 subunit alpha or Laminin-15 subunit alpha.

Components of the extracellular matrix exert myriad effects on tissues throughout the body. In particular, the laminins, a family of heterotrimeric extracellular glycoproteins, affect tissue development and integrity in such diverse organs as the kidney, lung, skin, and nervous system. It is thought that laminins mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminins function as heterotrimeric complexes of alpha, beta, and gamma chains, with each chain type representing a different subfamily of proteins. The protein encoded by this gene belongs to the alpha subfamily of laminin chains and is a major component of basement membranes. Two transcript variants encoding different isoforms have been found for this gene, but the full-length nature of one of them has not been determined.

Specifications

• Antigen: Laminin alpha-5
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: ascites with <0.1% sodium azide
• Gene Accession No.: O15230
• Gene Symbols: LAMA5
• Immunogen: Purified native Laminin alpha-5.
• Regulatory Status: RUO
• Gene ID (Entrez): 3911
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Immunoprecipitation, Immunocytochemistry
• Clone: 2D8/33
• Conjugate: Unconjugated
• Gene: LAMA5
• Gene Alias: [a]5; AA408760; AA408762; AI853660; KIAA0533; KIAA1907; LAMA5; laminin alpha-5 chain; laminin subunit alpha 5; laminin subunit alpha-5; laminin, alpha 5; laminin-10 subunit alpha; Laminin-11 subunit alpha; laminin-15 subunit alpha; laminin-511; mKIAA0533; RP11-157P1.6
• Host Species: Mouse
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a