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Laminin beta-2/gamma-1 Monoclonal Antibody (A5), Biotin, Invitrogen™

Catalog No. PIMA514646
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PIMA514646 500 μL
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Catalog No. PIMA514646 Supplier Thermo Scientific Supplier No. MA514646
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Description

Rat Monoclonal Antibody

MA5-14646 targets Laminin B2/gamma1 in IF, IHC (F), IHC (P, F), and IP applications and shows reactivity with Human and mouse samples. The MA5-14646 immunogen is mouse EHS laminin preparation.

Laminins are large heterotrimeric, noncollagenous glycoproteins composed of alpha, beta, and gamma chains. They are ubiquitously present in basement membrane (BM) along with entactin/nidogen (EN), collagen type IV (CIV), and large heparan sulfate proteoglycan (HSPG), which interact specifically with each other to form a continuous and regular BM. Alterations of BM integrity, from local discontinuities up to complete loss, are described in many types of human and animal epithelial neoplasms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Laminin beta-2/gamma-1
Applications Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation
Classification Monoclonal
Clone A5
Concentration 0.2 mg/mL
Conjugate Biotin
Formulation PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene LAMB2
Gene Accession No. P02468, P11047, P55268, Q61292
Gene Alias AA408497; AW211941; B2e; basement membrane protein; Lama; Lamb2; Lamb-2; Lamc1; Laminin B1s chain; laminin B2 chain; laminin beta 2; laminin beta 2 chain; laminin chain B3; laminin chain beta 2; laminin gamma 1 chain; Laminin S; laminin subunit beta 2; laminin subunit beta-2; laminin subunit gamma 1; laminin subunit gamma-1; laminin, beta 2; laminin, beta 2 (laminin S); laminin, gamma 1; laminin, gamma 1 (formerly LAMB2); laminin-1 subunit gamma; Laminin-10 subunit gamma; laminin-11 subunit beta; Laminin-11 subunit gamma; laminin-14 subunit beta; Laminin-15 subunit beta; laminin-2 subunit gamma; Laminin-3 subunit beta; laminin-3 subunit gamma; Laminin-4 subunit beta; laminin-4 subunit gamma; Laminin-6 subunit gamma; laminin-7 subunit beta; Laminin-7 subunit gamma; laminin-8 subunit gamma; Laminin-9 subunit beta; laminin-9 subunit gamma; LAMS; NPHS5; npht; SLAM; S-LAM beta; S-LAM gamma; S-laminin subunit beta; S-laminin subunit gamma
Gene Symbols LAMB2, LAMC1
Host Species Rat
Immunogen Murine EHS laminin preparation
Purification Method Protein G
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16779, 226519, 3913, 3915
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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