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Laminin Beta 2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501987788
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50-198-7788 100 μL
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Catalog No. 50-198-7788 Supplier Bioss Supplier No. BS7504R
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Description

Rabbit Polyclonal Antibody

Nuclear lamins form a network of intermediate-type filaments at the nucleoplasmic site of the nuclear membrane. Two main subtypes of nuclear lamins can be distinguished, i.e. A-type lamins and B-type lamins. The A-type lamins comprise a set of three proteins arising from the same gene by alternative splicing, i.e. lamin A, lamin C and lamin Adel 10, while the B-type lamins include two proteins arising from two distinct genes, i.e. lamin B1 and lamin B2. Recent evidence has revealed that mutations in A-type lamins give rise to a range of rare but dominant genetic disorders, including Emery-Dreifuss muscular dystrophy, dilated cardiomyopathy with conduction-system disease and Dunnigan-type familial partial lipodystrophy. In addition, the expression of A-type lamins coincides with cell differentiation and as A-type lamins specifically interact with chromatin, a role in the regulation of differential gene expression has been suggested for A-type lamins.

Specifications

Antigen Laminin Beta 2
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene LAMB2
Gene Accession No. P55268
Gene Alias LAMB2; Laminin B1s chain; laminin S; laminin subunit beta 2; Laminin subunit beta-2; laminin, beta 2 (laminin S); Laminin-11 subunit beta; Laminin-14 subunit beta; Laminin-15 subunit beta; Laminin-3 subunit beta; Laminin-4 subunit beta; Laminin-7 subunit beta; Laminin-9 subunit beta; LAMS; NPHS5; S-LAM beta; S-laminin subunit beta
Gene Symbols LAMB2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Laminin Beta 2.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3913
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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