Invitrogen™ Laminin gamma-1,2,3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA579576

Catalog No. PIPA579576

Description

This antibody reacts will all 3 isoforms of Laminin gamma: Laminin gamma-1, gamma-2 and gamma-3. Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human A431 whole cell, human A549 whole cell, human PC-3 whole cell, human CACO-2 whole cell, rat NRK whole cell, rat RH35 whole cell, mouse NIH/3T3 whole cell, mouse HEPA1-6 whole cell. IHC: mouse heart tissue, mouse kidney tissue, rat cardiac muscle tissue, rat kidney tissue.

Extracellular matrix (ECM) surrounds and separates most tissue compartments, determines tissue architecture and dynamically interacts with its surrounding cells. The basement membrane is a part of the ECM and is composed of collagens, proteoglycans, elastin and several glycoproteins of which laminin is the most abundant. Laminins are large heterotrimeric, noncollagenous glycoproteins composed of alpha, beta, and gamma chains Dystroglycan is a major laminin receptor in muscle and epithelia, and nidogen is a high-affinity laminin-binding protein important for basement-membrane assembly.

Specifications

• Antigen: Laminin gamma-1,2,3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LAMC1
• Gene Alias: AA589349; AI562206; alternatively spliced laminin gamma2 chain; AW240805; B2e; B2T; BM600; BM600-100kDa; cell-scattering factor 140 kDa subunit; CSF; CSF 140 kDa subunit; EBR2; EBR2A; epiligrin subunit gamma; Kalinin subunit gamma; kalinin/nicein/epiligrin 100 kDa subunit; Ladsin 140 kDa subunit; LAMB2; LAMB2T; LAMC1; Lamc2; Lamc3; lamimin, gamma 2; laminin B2 chain; Laminin B2t chain; laminin gamma 3; laminin gamma2 chain; laminin subunit gamma 1; laminin subunit gamma 2; laminin subunit gamma 3; laminin subunit gamma-1; Laminin subunit gamma-2; laminin subunit gamma-3; laminin, gamma 1; laminin, gamma 1 (formerly LAMB2); laminin, gamma 2; laminin, gamma 3; laminin-1 subunit gamma; Laminin-10 subunit gamma; laminin-11 subunit gamma; Laminin-12 subunit gamma; laminin-14 subunit gamma; Laminin-15 subunit gamma; laminin-2 subunit gamma; Laminin-3 subunit gamma; laminin-4 subunit gamma; Laminin-5 subunit gamma; laminin-6 subunit gamma; Laminin-7 subunit gamma; laminin-8 subunit gamma; Laminin-9 subunit gamma; LAMNB2; Large adhesive scatter factor 140 kDa subunit; nicein subunit gamma; nicein, 100kD; nicein, 100kDa; OCCM; S-LAM gamma; S-laminin subunit gamma
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10319, 117036, 16782, 192362, 226519, 23928, 311862, 3915, 3918
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and 0.05mg sodium azide
• Gene Accession No.: P02468, P11047, Q13753, Q61092, Q9R0B6, Q9Y6N6
• Gene Symbols: LAMC1, LAMC2, LAMC3
• Immunogen: Peptide mixture of laminin gamma1,2,3 (NKLNEIEGSLNKAKDEMKAS; DLEERVRRQRNHLHLLETSI; LQLDSHGALHHKLRQLEEES).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov