Invitrogen™ Laminin gamma-3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA554610

Catalog No. PIPA554610

Description

Immunogen sequence: CLPCNCSGRS EECTFDRELF RSTGHGGRCH HCRDHTAGPH CERCQENFYH WDPRMPCQPC DCQSAGSLHL QCDDTGTCAC KPTVTGWKCD RCLPGFHSLS EGGCRPCTCN PAGSLDTCDP RSGRCPCKEN VEG Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 83%.

Laminin is a non-collagenous protein of basement membranes. By rotary shadowing it has a cross-like shape, consisting of one long arm, (400 kD) and three short arms (200 kD). Antibodies to laminin localize exclusively in basement membranes. Laminin is found throughout the basement membrane, but the reaction with the antibodies to laminin is more intense in the lamina lucida, the part of the basement membrane adjacent to the cell membrane. Laminin binds to type IV collagen, a component exclusively localized in the basement membrane. Laminin has been shown to play a role in cell adhesion and attachment in vivo and in vitro.

Specifications

• Antigen: Laminin gamma-3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LAMC3
• Gene Alias: AI562206; AW240805; Lamc3; laminin gamma 3; Laminin gamma3; laminin subunit gamma 3; laminin subunit gamma-3; laminin, gamma 3; laminin-12 subunit gamma; Laminin-14 subunit gamma; laminin-15 subunit gamma; OCCM
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10319
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9Y6N6
• Gene Symbols: LAMC3
• Immunogen: Recombinant protein corresponding to Human Laminin gamma-3. Recombinant protein control fragment (Product #RP-102087).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG