Invitrogen™ LAMTOR2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA538033

Catalog No. PIPA538033

Description

A recommended positive control is HepG2 cell lysate. At least two isoforms of LAMTOR2 are known to exist; this antibody will detect both isoforms. LAMTOR2 antibody is not expected to cross-react with other LAMTOR family proteins.

The late endosomal/lysosomal adaptor MAPK and MTOR activator 2 (LAMTOR2) protein belongs to the LAMTOR family of proteins, and together with LAMTOR3 and the MAPK1 and ERK kinase 1 (MEK1) localizes to late endosomes where it is required for the efficient activation of ERK signaling. This complex is involved in the regulation of late endosomal traffic and cellular proliferation and plays a role in cellular host defense against Salmonella infection.

Specifications

• Antigen: LAMTOR2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LAMTOR2
• Gene Alias: 2010111E04Rik; AL022628; ENDAP; Endosomal adaptor protein p14; HSPC003; LAMTOR2; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2; late endosomal/lysosomal adaptor, MAPK and MTOR activator 2; late endosomal/lysosomal MP1 interacting protein; late endosomal/lysosomal Mp1-interacting protein; MAPBP-interacting protein; Mapbpip; MAPKSP1 adaptor protein; MAPKSP1AP; mitogen activated protein binding protein interacting protein; mitogen-activated protein binding protein interacting protein; mitogen-activated protein-binding protein-interacting protein; mitogen-activated protein-binding protein-interacting protein (MAPBPIP); P14; Rab25; ragulator complex protein LAMTOR2; Ragulator2; RGD1562501; roadblock domain containing 3; roadblock domain-containing protein 3; ROBLD3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 28956, 295234, 83409
• Content And Storage: Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q9JHS3, Q9Y2Q5
• Gene Symbols: LAMTOR2
• Immunogen: 18 amino acid peptide near the center of human LAMTOR2.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov