Invitrogen™ LAMTOR4 Polyclonal Antibody

Catalog No.	Quantity
PIPA5114923	100 μL

Catalog No. PIPA5114923 Supplier Invitrogen™ Supplier No. PA5114923

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total C7orf59.

LAMTOR4 is a part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. LAMTOR4 is activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. LAMTOR4 is activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated.

Specifications

• Antigen: LAMTOR4
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene: LAMTOR4
• Gene Accession No.: Q0VGL1
• Gene Alias: 0910001L09Rik; AV006840; C7orf59; Lamtor4; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 4; late endosomal/lysosomal adaptor, MAPK and MTOR activator 4; ragulator complex protein LAMTOR4; Ragulator complex protein LAMTOR4, N-terminally processed; RGD1309735; UPF0539 protein C7orf59; UPF0539 protein C7orf59 homolog
• Gene Symbols: LAMTOR4
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human LAMTOR4(Accession Q0VGL1), corresponding to amino acid residues E10-N60.
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 360776, 389541
• Target Species: Human, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG