Invitrogen™ LAMTOR4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA554301

Catalog No. PIPA554301

Description

Immunogen sequence: MTSALTQGLE RIPDQLGYLV LSEGAVLASS GDLENDEQAA SAISELVSTA CGFRLHRGMN VPFKRLSVVF GEHTLLVTVS GQRVFVVKRQ NRGREPIDV Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 97%.

LAMTOR4 is a part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. LAMTOR4 is activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. LAMTOR4 is activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated.

Specifications

• Antigen: LAMTOR4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LAMTOR4
• Gene Alias: 0910001L09Rik; AV006840; C7orf59; Lamtor4; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 4; late endosomal/lysosomal adaptor, MAPK and MTOR activator 4; ragulator complex protein LAMTOR4; Ragulator complex protein LAMTOR4, N-terminally processed; RGD1309735; UPF0539 protein C7orf59; UPF0539 protein C7orf59 homolog
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 389541
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q0VGL1
• Gene Symbols: LAMTOR4
• Immunogen: Recombinant protein corresponding to Human LAMTOR4. Recombinant protein control fragment (Product #RP-92832).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG