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Langerin/CD207 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501984873
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50-198-4873 100 μL
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Catalog No. 50-198-4873 Supplier Bioss Supplier No. BS2650R
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Description

Rabbit Polyclonal Antibody

Langerin (CD207) is a type II membrane-associated C-type lectin known to be expressed exclusively by Langerhans cells. Lamgerin recognizes mannose residues via its single carbohydrate recognition domain (CRD). Langerin is localized not only on the cell surface, but also intracellularly in close association with Birbeck granules. Transfection of Langerin cDNA into fibroblasts creates a compact network of membrane structures with typical features of Birbeck granules (BG). Langerin is thus a potent inducer of membrane superimposition and zippering leading to BG formation.

Specifications

Antigen Langerin/CD207
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene CD207
Gene Accession No. Q9UJ71
Gene Alias Cd207; CD207 antigen; CD207 antigen, langerin; CD207 molecule; CD207 molecule, langerin; CLEC4K; C-type lectin domain family 4 member K; C-type lectin domain family 4, member K; Langerhans cell specific c-type lectin; Langerin
Gene Symbols CD207
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human CD207.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 50489
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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