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Invitrogen™ Langerin Monoclonal Antibody (2E1B2)
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Catalog No. PIMA538473
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100 μg
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Catalog No. Quantity
PIMA538473 100 μg
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Catalog No. PIMA538473 Supplier Invitrogen™ Supplier No. MA538473
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Description

Mouse Monoclonal Antibody

This antibody has been tested in indirect ELISA.

Langerin (CD207) is a type II membrane-associated C-type lectin known to be expressed exclusively by Langerhans cells. Lamgerin recognizes mannose residues via its single carbohydrate recognition domain (CRD). Langerin is localized not only on the cell surface, but also intracellularly in close association with Birbeck granules. Transfection of Langerin cDNA into fibroblasts creates a compact network of membrane structures with typical features of Birbeck granules (BG). Langerin is thus a potent inducer of membrane superimposition and zippering leading to BG formation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Langerin
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 2E1B2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene CD207
Gene Accession No. Q9UJ71
Gene Alias CD 207 antigen; CD207; CD207 antigen; CD207 antigen, langerin; CD207 molecule; CD207 molecule, langerin; CLEC4K; C-type lectin domain family 4 member K; C-type lectin domain family 4, member K; Langerhans cell specific c-type lectin; langerin; RGD1565913
Gene Symbols CD207
Host Species Mouse
Immunogen Purified recombinant fragment of human CD207 (aa: 65-328) expressed in E. Coli.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 50489
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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