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Invitrogen™ Langerin Polyclonal Antibody
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Catalog No. PIPA530722
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100 μL
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PIPA530722 100 μL
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Catalog No. PIPA530722 Supplier Invitrogen™ Supplier No. PA530722
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: A549, HeLa, HepG2, C8D30, NIH-3T3, C2C12. Predicted reactivity: Human (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Langerin (CD207) is a type II membrane-associated C-type lectin known to be expressed exclusively by Langerhans cells. Lamgerin recognizes mannose residues via its single carbohydrate recognition domain (CRD). Langerin is localized not only on the cell surface, but also intracellularly in close association with Birbeck granules. Transfection of Langerin cDNA into fibroblasts creates a compact network of membrane structures with typical features of Birbeck granules (BG). Langerin is thus a potent inducer of membrane superimposition and zippering leading to BG formation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Langerin
Applications Western Blot
Classification Polyclonal
Concentration 0.94 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene CD207
Gene Accession No. Q8VBX4, Q9UJ71
Gene Alias CD 207 antigen; CD207; CD207 antigen; CD207 antigen, langerin; CD207 molecule; CD207 molecule, langerin; CLEC4K; C-type lectin domain family 4 member K; C-type lectin domain family 4, member K; Langerhans cell specific c-type lectin; langerin; RGD1565913
Gene Symbols CD207
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the Extracellular domain of human Langerin. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 246278, 50489
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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